Locus TA04749

Locus

ID TA04749 genomic context (Gviz / IGV.js)
genomic context
Family SymE/SymR
Organism Escherichia coli str. K-12 substr. MG1655
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia; Escherichia coli str. K-12 substr. MG1655
Genomic location chromosome
Genomic coordinates 4579464-4579917
Genome accession (GenBank) NC_000913.3
Genome map CGView
Genomic context IGV.js
Upstream gene mcrB : 5-methylcytosine-specific restriction enzyme subunit McrB
Within-locus gene symE : nucleoid-associated protein SymE
symR : small regulatory RNA antitoxin SymR
Downstream gene hsdS : type I restriction enzyme EcoKI specificity subunit

Toxin mRNA

Name SymE predicted 2D structure (mfold / VARNA)
mRNA structure
Locus_tag
Genomic coordinates 4579464-4579917 (strand -)
Length 454 nt
Sequence
(with 50 nt upstream, and -10 box in red; mRNA/asRNA interaction region underlined; toxin ORF in blue; transcript sequence in UPPERCASE)
tattctatttttagctggactttccccatatttactgatgatatatacag
GTATTTAGCGCGGTGCGGATGTGCGCCAACACACCCGCATCGCTAATCAC
AATCACTATTCCTGGAGAATAGCAGTTATGACTGACACGCATTCTATTGC
ACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCATGTCACCG
TCGGTTATGCGAGTCGCTACCCGGATTACAGCCGTATTCCCGCCATCACC
CTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCCACTGGCACGGCGGT
AGATGTCAAAGTGATGGAAGGCTGTATTGTCCTCACCGCCCAACCACCCG
CCGCCGAGGAGAGCGAACTGATGCAGTCGCTACGCCAGGTGTGCAAACTG
TCGGCGCGTAAACAAAAGCAGGTGCAGGCGTTTATTGGAGTGATTGCCGG
TAAACAGAAAGTCGCGTAACAGCGTTTACTCCCGGTTAACCACCGGGAGC
CTTC
→ BLAST sequence
Predicted 2D structure PDF, PNG

Antitoxin asRNA

Name SymR predicted 2D structure (mfold / VARNA)
sRNA structure
Locus_tag
Genomic coordinates 4579835-4579911 (strand +)
Length 77 nt
Sequence
(with 50 nt upstream, and -10 box in red; transcript sequence in UPPERCASE)
tttgccggggagacttctgcttcgaacggttgtgcaatagaatgcgtgtc
AGTCATAACTGCTATTCTCCAGGAATAGTGATTGTGATTAGCGATGCGGG
TGTGTTGGCGCACATCCGCACCGCGCT
→ BLAST sequence
Predicted 2D structure PDF, PNG

Toxin Peptide

Name SymE predicted 2D structure (PSIPRED / POLYVIEW-2D)
peptide structurepeptide structure legend

hydrophobicity plot (ProtScale)
peptide hydrophobicity
Locus_tag
ORF genomic coordinates 4579499-4579840 (strand -)
ORF length (peptide length) 342 nt (113 aa)
ORF sequence
ATGACTGACACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCC
GGCAAATAACCGTCATGTCACCGTCGGTTATGCGAGTCGCTACCCGGATT
ACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCC
GGTTTTGCCACTGGCACGGCGGTAGATGTCAAAGTGATGGAAGGCTGTAT
TGTCCTCACCGCCCAACCACCCGCCGCCGAGGAGAGCGAACTGATGCAGT
CGCTACGCCAGGTGTGCAAACTGTCGGCGCGTAAACAAAAGCAGGTGCAG
GCGTTTATTGGAGTGATTGCCGGTAAACAGAAAGTCGCGTAA
→ BLAST sequence
Peptide sequence
MTDTHSIAQPFEAEVSPANNRHVTVGYASRYPDYSRIPAITLKGQWLEAA
GFATGTAVDVKVMEGCIVLTAQPPAAEESELMQSLRQVCKLSARKQKQVQ
AFIGVIAGKQKVA*
→ BLAST sequence
Predicted 2D structure PDF, GIF
Hydrophobicity plot PDF, GIF